What we do
Stem cells reside at the apex of a differentiation hiearchy and potentially give rise to a multitude of cells that compose a single tissue system. Our lab primarily focuses on the study of tissue stem cells, especially hematopoietic stem cells. Our investigation aims to delineate the mechanisms of how stem cells are regulated endogenously as well as exogenously through interactions with their surrounding microenvironment (niche). We wish to achieve this through the appreciation of tissue and cell morphology and integration of functional analyses to gain a novel view regarding the regulation of stem cells and a tissue system.
Click here for an overview of the main course at Tokyo Women's Medical University School of Medicine.(Japanese)
Hematopoietic stem cell regulation through the bone marrow niche CLICK FOR REVIEW IN DEVELOPMENT
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Development 2014 |
Mitochondria in hematopoietic stem cell differentiation CLICK FOR PAPER IN CELL REPORTS
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Cell Reports 2018 |
Hematopoietic stem cell regulation by the cytokine Thrombopoietin CLICK FOR REVIEW IN NYAS
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Annals NY A Sci. 2018 |
Tokyo Women's Medical University
Department of Microscopic Anatomy and Developmental Biology 8-1 Kawada-cho Shinjyuku-ku
Education & reserach building, 5F 162-8666, Tokyo, Japan Tokyo Women's Medical University(English) |